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Search Results for " protein phosphatase inhibitor 1 "
Targets Recommended: Phosphatase

30

抑制剂 & 化合物

6

天然产物

4

TargetMol 试剂盒

1736

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Cat. No. Product Name Form Specificity Of Inhibition
C0045 RIPA Lysis Buffer (Strong)

RIPA裂解液(强)

Solution in bottle
C0046 RIPA Lysis Buffer (Middle)

RIPA裂解液(中)

Solution in bottle
C0047 RIPA Lysis Buffer (Weak)

RIPA裂解液(弱)

Solution in bottle
C0003 Phosphatase Inhibitor Cocktail II (100× DMSO)

磷酸酶抑制剂 Cocktail II (100× DMSO)

Solution (<em>1</em>00× in DMSO) Alkaline <em>phosphatase</em>s, Ser/Thr <em>phosphatase</em>s, Acid and PP<em>1</em> and PP2A

TargetMol 试剂盒

RIPA裂解液(强)
Cat.No: C0045
RIPA裂解液(中)
Cat.No: C0046
RIPA裂解液(弱)
Cat.No: C0047
磷酸酶抑制剂 Cocktail II (100× DMSO)
Cat.No: C0003
Cat. No. Product Name Target Signaling Pathways
T7541 PTP inhibitor 1

PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮

Phosphatase Metabolism
PTP inhibitor 1 是蛋白酪氨酸磷酸酶 (PTP) 抑制剂,具有抗血管生成作用。
T9174 Icerguastat

Sephin 1,lcerguastat,IFB-088

Phosphatase Metabolism
Icerguastat (IFB-088) 是一种缺乏 α2-肾上腺素能活性的 Guanabenz 衍生物,是一种磷酸酶调节亚单位 PPP1R15A (R15A)的选择性抑制剂。它能够抑制 eIF2α 去磷酸化,从而延长保护反应。它具有抗朊病毒作用。
T21824 Sephin1

NSC 65390,IFB-088

Phosphatase Metabolism
Sephin1 (IFB-088) 是 GADD34 (PPP1R15A) 的选择性抑制剂,这是一种应激诱导的蛋白磷酸酶 1 复合物调节亚基,可将 eIF2α 去磷酸化。
T7356 PTP1B-IN-1

PTP1B inhibitor,5-苯基-1,2,5-噻二唑烷-3-酮 1,1-二氧化物

Phosphatase Metabolism
PTP1B-IN-1 (PTP1B inhibitor) 是一种蛋白质酪氨酸磷酸酶 1B 的有效抑制剂 (IC50 : 1.6 mM)
T28804 Slingshot inhibitor D3

JHN76359

Others Others
Slingshot inhibitor D3 (JHN76359) 是具有选择性、竞争性、可逆性的Slingshot 抑制剂。它对Slingshot 1和Slingshot 2具有相似的抑制活性。它对Slingshot 1 的IC50为 3 μM;对Slingshot 2 的Ki 为 3.9 μM。
T13013 Sodium stibogluconate

Stibogluconate trisodium nonahydrate,葡萄糖酸锑钠

Phosphatase Metabolism
Sodium stibogluconate (Stibogluconate trisodium nonahydrate) 是一种有效的蛋白酪氨酸磷酸酶 (phosphatase) 抑制剂。 它在10,100 和 100 μg/mL 时分别抑制 99% 的 SHP-1,SHP-2 和 PTP1B 活性。
T10927 Cyt-PTPε Inhibitor-1

Cyt-PTP|A Inhibitor-1

Phosphatase; Src Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
Cyt-PTPε Inhibitor-1 (A Inhibitor-1) 是胞质蛋白酪氨酸磷酸酶 ε 的抑制剂。 Cyt-PTPε Inhibitor-1 阻断 c-Src 的去磷酸化并表现出抗破骨活性。
T4491 LMPTP INHIBITOR 1 hydrochloride

LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))

Phosphatase Metabolism
LMPTP INHIBITOR 1 hydrochloride 是一种高选择性的低分子量蛋白酪氨酸磷酸酶 (LMPTP) 抑制剂。LMPTP INHIBITOR 1 (hydrochloride) 能够抑制 LMPTP-A 的活性,IC50值为 0.8 μM。
T7084 2-Bromo-4'-hydroxyacetophenone

SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮

Phosphatase Metabolism
2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) 是一种PTP1B 的有效抑制剂,其Ki=42 μM。
T41298 LMPTP INHIBITOR 1 dihydrochloride

Phosphatase Metabolism
LMPTP INHIBITOR 1 dihydrochloride 是选择性的低分子量蛋白酪氨酸磷酸酶(LMPTP)抑制剂,抑制 LMPTP-A 活性的IC50为 0.8 μM。
T81417 PP5-IN-1

Apoptosis; Phosphatase Apoptosis; Metabolism
PP5-IN-1 是一种具有有效性和竞争性的丝氨酸/苏氨酸蛋白磷酸酶-5 (PP5) 抑制剂,具有潜在的抗癌活性,可诱导癌细胞凋亡。
T14859 Calyculin A

(-)-Calyculin A

Others Others
Calyculin A is a potent and cell-permeable inhibitor of protein phosphatase 1 (PP1; IC50s: 2 nM). It also is a protein phosphatase 2A (PP2A) inhibitor (IC50s: 0.5-1 nM).
T70441 1E7-03

1E7-03 is an inhibitor of HIV-1 transcription, by targeting host Protein Phosphatase-1 (PP1).
T12116 MSI-1436

Aminosterol-1436,Trodusquemine

Others Others
MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)
T12117 MSI-1436 lactate

Trodusquemine lactate,Aminosterol-1436 lactate

Others Others
MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)
T35777 Nodularin

The cyanobacterium Nodularia spumigena often contaminates the drinking water of rural communities in developing countries and accumulates in mussels, flounder, and cod from the northern Baltic Sea. Nodularin is a hepatotoxic monocylic pentapeptide produced by the N. spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC50 values of 1.8 and 0.026 nM, respectively. PP2B is inhibited to a lesser extent with an IC50 of 1.8 μM. No apparent inhibitory eff...
T83530 LB-100

(Rac)-LB-100为LB-100的外消旋体,系一种蛋白磷酸酶2A(PP2A)抑制剂。
T75738 Microcystin-RR

Microcystin-RR (Cyanoviridin RR),一种有效的口服活性蛋白磷酸酶抑制剂,能诱导细胞凋亡和小鼠肝脏内质网应激。
T80870 VE-PTP-IN-1

VE-PTP-IN-1 (compound 2) 为一种选择性VE-PTP抑制剂,呈弱酸性,涉及调控血管稳态及血管生成。
T61851 PTP1B-IN-3 diammonium

PTP1B-IN-3 diammonium is a highly effective and orally bioavailable inhibitor of the protein tyrosine phosphatase 1B (PTP1B) enzyme, with an IC50 value of 120 nM for both PTP1B and TCPTP. This compound exhibits potent antidiabetic and anticancer properties, as supported by extensive research [1] [2].
T78702 PTP1B/AKR1B1-IN-1

Phosphatase Metabolism
PTP1B/AKR1B1-IN-1是一种针对PTP1B和AKR1B1的双重抑制剂,其IC50值分别为0.06 μM和4.3 μM。该化合物也能抑制TC-PTP,IC50为9 μM。在小鼠成肌细胞中,PTP1B/AKR1B1-IN-1作为胰岛素模拟剂使用,并能减少AKR1B1依赖的山梨醇积累,有助于抑制2型糖尿病的发展并控制血糖水平。
T75864 Calcineurin autoinhibitory peptide TFA

Calcineurin autoinhibitory peptide TFA 为选择性Ca2+/钙调蛋白依赖性蛋白磷酸酶(钙调神经磷酸酶)抑制剂,IC50约为10 μM。该化合物能够保护神经元不受兴奋性神经元死亡影响。
T73120 MptpB-IN-1

MptpB-IN-1 是一种有效的、具有口服活性的 MptpB 抑制剂。结核分枝杆菌蛋白-酪氨酸-磷酸酶 B (MptpB) 是一种分泌的毒力因子,可破坏宿主的抗菌活性。MptpB-IN-1 可降低耐多药结核分枝杆菌的存活率和感染负担。
T78611 SHP2-IN-5

SHP2-IN-5(化合物1)为SHP2抑制剂,IC50为97 nM。SHP2,一种非受体型蛋白酪氨酸磷酸酶,与细胞生长及增殖紧密相关。SHP2-IN-5可能对抑制癌症和其他与SHP2有关的疾病具有治疗潜力。
T74980 SPAA-52

SPAA-52 是一种具有口服活性的、竞争性的和可逆的低分子量蛋白酪氨酸磷酸酶 (LMW-PTP) 抑制剂 (IC50=4 nM,Ki=1.2 nM)。SPAA-52 可用于糖尿病的研究。
T35806 N-Stearoylsphingosine

C(18:0)/C(18:1),Cer(d18:1/18:0),C18 Ceramide (d18:1/18:0),C18 Ceramide

Phosphatase Metabolism
N-Stearoylsphingosine (Cer(d18:1/18:0)) 是一种广泛存在真核生物体内的酰胺类化合物,通过干扰PP2A与PP2A抑制剂2的结合来增强蛋白质磷酸酶2A(PP2A)活性,导致Akt去磷酸化。N-Stearoylsphingosine 可用于研究前列腺癌。
T37056 D-erythro-MAPP

D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 μM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner.
T41370 (Rac)-RK-682

(Rac)-RK-682 是 RK-682 的外消旋体。(Rac)-RK-682 是一种蛋白质酪氨酸磷酸酶 (PTPases) 抑制剂。(Rac)-RK-682 抑制蛋白酪氨酸磷酸酶 1B (PTP-1B)、低分子量蛋白酪氨酸磷酸酶 (LMW-PTP)、细胞分裂周期 25B (CDC-25B),IC50分别为 8.6 μM、12.4 μM 和 0.7 μM。
T79479 MptpB-IN-2

Antibiotic Microbiology/Virology
MptpB-IN-2(化合物20)是一种高选择性的结核分枝杆菌蛋白酪氨酸磷酸酶B(MptpB)抑制剂,其对MptpB、MptpA和PTP1B的IC50值分别为0.64 μM、4.06 μM和4.14 μM。此化合物对Mtb H37Rv表现出较低的抗结核活性,MIC为64.9 μM。
T83857 Soluble Epoxide Hydrolase PROTAC 1a

sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a

Soluble epoxide hydrolase (sEH) PROTAC 1a是一种利用蛋白质降解靶向嵌合体(PROTAC)技术,通过连接区域将cereblon配体1与sEH抑制剂t-TUCB结合。该化合物通过促进sEH的降解,特异性抑制sEH的水解酶活性(IC50 = 0.8 nM),相较于其磷酸酶活性(IC50 = >10,000 nM)具有较高选择性。sEH PROTAC 1a还特定促进细胞质中而非过氧体中的sEH降解,并通过溶酶体而非蛋白酶体实现其降解。它能够降低thapsigargin诱导的HepG2与293T细胞中磷酸化的inositol-requiring enzyme 1α (IRE1α)水平和X-box结合蛋白1 (XBP1)剪接,表明能减少ER应激。

化合物

PTP inhibitor 1
Cat.No: T7541
Synonym: PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮
Target: Phosphatase
Icerguastat
Cat.No: T9174
Synonym: Sephin 1,lcerguastat,IFB-088
Target: Phosphatase
Sephin1
Cat.No: T21824
Synonym: NSC 65390,IFB-088
Target: Phosphatase
PTP1B-IN-1
Cat.No: T7356
Synonym: PTP1B inhibitor,5-苯基-1,2,5-噻二唑烷-3-酮 1,1-二氧化物
Target: Phosphatase
Slingshot inhibitor D3
Cat.No: T28804
Synonym: JHN76359
Target: Others
Sodium stibogluconate
Cat.No: T13013
Synonym: Stibogluconate trisodium nonahydrate,葡萄糖酸锑钠
Target: Phosphatase
Cyt-PTPε Inhibitor-1
Cat.No: T10927
Synonym: Cyt-PTP|A Inhibitor-1
Target: Phosphatase, Src
LMPTP INHIBITOR 1 hydrochloride
Cat.No: T4491
Synonym: LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))
Target: Phosphatase
2-Bromo-4'-hydroxyacetophenone
Cat.No: T7084
Synonym: SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮
Target: Phosphatase
LMPTP INHIBITOR 1 dihydrochloride
Cat.No: T41298
Synonym:
Target: Phosphatase
PP5-IN-1
Cat.No: T81417
Synonym:
Target: Apoptosis, Phosphatase
Calyculin A
Cat.No: T14859
Synonym: (-)-Calyculin A
Target: Others
1E7-03
Cat.No: T70441
Synonym:
Target:
MSI-1436
Cat.No: T12116
Synonym: Aminosterol-1436,Trodusquemine
Target: Others
MSI-1436 lactate
Cat.No: T12117
Synonym: Trodusquemine lactate,Aminosterol-1436 lactate
Target: Others
Nodularin
Cat.No: T35777
Synonym:
Target:
LB-100
Cat.No: T83530
Synonym:
Target:
Microcystin-RR
Cat.No: T75738
Synonym:
Target:
VE-PTP-IN-1
Cat.No: T80870
Synonym:
Target:
PTP1B-IN-3 diammonium
Cat.No: T61851
Synonym:
Target:
PTP1B/AKR1B1-IN-1
Cat.No: T78702
Synonym:
Target: Phosphatase
Calcineurin autoinhibitory peptide TFA
Cat.No: T75864
Synonym:
Target:
MptpB-IN-1
Cat.No: T73120
Synonym:
Target:
SHP2-IN-5
Cat.No: T78611
Synonym:
Target:
SPAA-52
Cat.No: T74980
Synonym:
Target:
N-Stearoylsphingosine
Cat.No: T35806
Synonym: C(18:0)/C(18:1),Cer(d18:1/18:0),C18 Ceramide (d18:1/18:0),C18 Ceramide
Target: Phosphatase
D-erythro-MAPP
Cat.No: T37056
Synonym:
Target:
(Rac)-RK-682
Cat.No: T41370
Synonym:
Target:
MptpB-IN-2
Cat.No: T79479
Synonym:
Target: Antibiotic
Soluble Epoxide Hydrolase PROTAC 1a
Cat.No: T83857
Synonym: sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a
Target:
Cat. No. Product Name Target Signaling Pathways
T3S1612 kuwanon G

桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂,具有杀菌作用。
T23421 Tautomycetin

Others Others
protein phosphatase (PP)1 inhibitor
T70725 Motuporin

Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).
T75495 Rubrofusarin 6-O-β-D-glucopyranoside

Rubrofusarin 6-O-β-D-glucopyranoside为Rubrofusarin的糖苷形式,具有抑制蛋白酪氨酸磷酸酶 1B (PTP1B) 的活性,IC50值为87.36 μM,适用于糖尿病和抑郁症研究。
T79985 Cryptosporioptide A

Phosphatase Metabolism
Cryptosporioptide A (Compound 3)是一种从昆虫寄生真菌Cordyceps gracilioides中分离出的色素蛋白酪氨酸磷酸酶抑制剂,针对PTP1B、SHP2、CDC25B、LAR和SHP1等酶展示了抑制作用,其IC50值分别为7.3、5.7、7.6、>50、4.9 μg/mL。
T38069 Aquastatin A

Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K....

天然产物

kuwanon G
Cat.No: T3S1612
Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G
Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase
Tautomycetin
Cat.No: T23421
Synonym:
Target: Others
Motuporin
Cat.No: T70725
Synonym:
Target:
Rubrofusarin 6-O-β-D-glucopyranoside
Cat.No: T75495
Synonym:
Target:
Cryptosporioptide A
Cat.No: T79985
Synonym:
Target: Phosphatase
Aquastatin A
Cat.No: T38069
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00528 PPP1R1A Protein, Human, Recombinant (His)

PPP1R1A,I-1,IPP-1,Pr...

Human E. coli
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by cal...
TMPJ-01261 PPP1R14A Protein, Human, Recombinant (His)

17 kDa PKC-Potentiated Inhibitory Prot...

Human E. coli
Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase. PPP1R14A is the inhibitor of PPP1CA. When phosphorylated, PPP1R14A has over 1000-fold higher inhibitory activity, creating a molecular switch for regulating the phosphorylation status of PPP1CA su...
TMPY-02595 DUSP14 Protein, Human, Recombinant (His & MBP)

MKP6,MKP-L,dual specificity phosphatase 14

Human E. coli
Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosphotyrosine and phosphoserine / phosphothreonine residues in substrates. Unlike many other DUSPs, DUSP14 only contains a catalytic domain within the C-terminal region. In signal transduction, DUSP14 has been considered as negative regulator of the mitogen-activated protein kinase (...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...

Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RI...

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi)

ACE2,ACE-2,ACEH

Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-01147 R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

RSPO,CRISTIN3,R-spondin 1

Human HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His)

W282,W264,CEA,CD66D,CGM1,MGC11987...

Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-01938 CD98 Protein, Human, Recombinant (His)

4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...

Human HEK293 Cells
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPY-01894 SIGIRR Protein, Human, Recombinant (His)

TIR8,single immunoglobulin and toll-interleukin 1 r...

Human HEK293 Cells
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His)

ActRIIB,activin A receptor, type IIB,4930516B21...

Mouse HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-01258 IL-13RA1 Protein, Human, Recombinant (His)

NR4,interleukin 13 receptor, alpha 1,CD2

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His)

D1S166E,tumor necrosis factor receptor sup...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-00861 IL-33 Protein, Human, Recombinant

IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...

Human E. coli
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His)

FLK2,FLK-2,CD135,STK1,fms-related tyrosine...

Human HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-01185 DR5/TRAIL R2 Protein, Human, Recombinant (His)

KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His)

thymic stromal lymphopoietin

Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-06418 R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

R-spondin 2,CRISTIN2

Human HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 4

Human,Rhesus HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant

FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL

Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-01883 EPOR Protein, Human, Recombinant (His)

erythropoietin receptor,EPO-R

Human HEK293 Cells
EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1.
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)

WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...

Human HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant

LAG-3,lymphocyte-activation gene 3,CD223

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His)

ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...

Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc)

INCAM-100,CD106,VCAM-1,vascular c...

Human HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-04165 FGFR3 Protein, Human, Recombinant (His)

JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-01137 HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)

erb-b2 receptor tyrosine kinase 2,NEU,ENVW,HERV-7q,HERV7Q,HE...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His)

HHF5,CD220,insulin receptor

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-02033 CD44 Protein, Human, Recombinant (His)

CD44 molecule (Indian blood group),IN,MC56,HUTCH-I,MIC4,CDW4...

Human HEK293 Cells
CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1.
TMPY-01744 ACVR2A Protein, Human, Recombinant (His)

activin A receptor, type IIA,ACVR2,ACTRII

Human HEK293 Cells
ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1.
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His)

BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3

Human HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-01851 CD73 Protein, Human, Recombinant (His)

eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...

Human HEK293 Cells
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-01949 CD19 Protein, Human, Recombinant (His)

CD19 molecule,B4,CVID3

Human HEK293 Cells
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-00978 Progranulin Protein, Human, Recombinant (His)

PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...

Human HEK293 Cells
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-05208 PD-L1 Protein, Human, Recombinant

CD274 molecule,PDCD1L1,PD-L1,PDL<...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-00853 IL-1RA Protein, Human, Recombinant

DIRA,IL1RA,interleukin 1 receptor antagoni...

Human E. coli
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01862 IL-4 Protein, Human, Recombinant

Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF

Human E. coli
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His)

leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C

Human HEK293 Cells
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig...
TMPY-04333 LRRC15 Protein, Human, Recombinant (hFc)

leucine rich repeat containing 15,LIB

Human HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-03531 PSGL-1/CD162 Protein, Human, Recombinant (His)

selectin P ligand,PSGL-1,PSGL1,CD1

Human HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G1<...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S)

Ighg1,IgG1 Fc

Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
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重组蛋白

PPP1R1A Protein, Human, Recombinant (His)
Cat.No: TMPJ-00528
Species: Human
Expression System: E. coli
PPP1R14A Protein, Human, Recombinant (His)
Cat.No: TMPJ-01261
Species: Human
Expression System: E. coli
DUSP14 Protein, Human, Recombinant (His & MBP)
Cat.No: TMPY-02595
Species: Human
Expression System: E. coli
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03745
Species: Human
Expression System: HEK293 Cells
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00383
Species: Human
Expression System: HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01147
Species: Human
Expression System: HEK293 Cells
CEACAM3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01850
Species: Human
Expression System: HEK293 Cells
CD98 Protein, Human, Recombinant (His)
Cat.No: TMPY-01938
Species: Human
Expression System: HEK293 Cells
SIGIRR Protein, Human, Recombinant (His)
Cat.No: TMPY-01894
Species: Human
Expression System: HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01281
Species: Mouse
Expression System: HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01258
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His)
Cat.No: TMPY-01827
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
IL-33 Protein, Human, Recombinant
Cat.No: TMPY-00861
Species: Human
Expression System: E. coli
FLT3 Protein, Human, Recombinant (T227M, His)
Cat.No: TMPY-01247
Species: Human
Expression System: HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01185
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
Cat.No: TMPY-05220
Species: Human
Expression System: HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06418
Species: Human
Expression System: HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His)
Cat.No: TMPY-02813
Species: Human,Rhesus
Expression System: HEK293 Cells
FLT3 Ligand Protein, Human, Recombinant
Cat.No: TMPY-06873
Species: Human
Expression System: E. coli
EPOR Protein, Human, Recombinant (His)
Cat.No: TMPY-01883
Species: Human
Expression System: HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04970
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant
Cat.No: TMPY-04939
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04348
Species: Human
Expression System: HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00947
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04165
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
Cat.No: TMPY-01137
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
Cat.No: TMPY-01146
Species: Human
Expression System: HEK293 Cells
CD44 Protein, Human, Recombinant (His)
Cat.No: TMPY-02033
Species: Human
Expression System: HEK293 Cells
ACVR2A Protein, Human, Recombinant (His)
Cat.No: TMPY-01744
Species: Human
Expression System: HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03967
Species: Human
Expression System: HEK293 Cells
CD73 Protein, Human, Recombinant (His)
Cat.No: TMPY-01851
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (His)
Cat.No: TMPY-01949
Species: Human
Expression System: HEK293 Cells
Progranulin Protein, Human, Recombinant (His)
Cat.No: TMPY-00978
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant
Cat.No: TMPY-05208
Species: Human
Expression System: HEK293 Cells
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
IL-1RA Protein, Human, Recombinant
Cat.No: TMPY-00853
Species: Human
Expression System: E. coli
IL-4 Protein, Human, Recombinant
Cat.No: TMPY-01862
Species: Human
Expression System: E. coli
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
LILRB5/CD85c Protein, Human, Recombinant (His)
Cat.No: TMPY-04826
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04333
Species: Human
Expression System: HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His)
Cat.No: TMPY-03531
Species: Human
Expression System: HEK293 Cells
LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
Cat.No: TMPY-00820
Species: Human
Expression System: HEK293 Cells
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